Ibudilast is a pharmaceutical drug that is primarily used in the treatment of asthma and other respiratory conditions. It works by inhibiting certain enzymes in the body, such as phosphodiesterase and macrophage migration inhibitory factor (MIF), which are involved in inflammatory processes.
In addition to its anti-inflammatory properties, ibudilast has also shown potential therapeutic effects in other areas. Research suggests that it may have neuroprotective properties and could be useful in the treatment of neurological disorders such as multiple sclerosis (MS). It is believed to work by suppressing inflammatory responses within the central nervous system.
Furthermore, ibudilast has been explored for its potential use in substance abuse disorders. Preliminary studies have shown that it may reduce cravings and withdrawal symptoms associated with opioid addiction, as well as suppress alcohol-induced neuroinflammation.
While ibudilast has demonstrated promising effects in preclinical and early clinical trials, further research is still needed to fully understand its mechanisms of action and determine its efficacy and safety across different applications.